RhoGTPase-binding proteins, the exocyst complex and polarized vesicle trafficking
نویسندگان
چکیده
منابع مشابه
The exocyst complex in polarized exocytosis.
The exocyst is an octameric protein complex, which mediates the tethering of post-Golgi secretory vesicles to the plasma membrane before exocytic fusion. The exocyst assembles by side-by-side packing of rod-shaped subunits composed of helical bundles. The targeting of secretory vesicles to the plasma membrane involves direct interactions of the exocyst with PI(4,5)P(2). In addition, a number of...
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ژورنال
عنوان ژورنال: Small GTPases
سال: 2014
ISSN: 2154-1248,2154-1256
DOI: 10.4161/sgtp.28453